![]() ![]() Instead, pheochromocytoma may be asymptomatic or may include symptoms mainly of the cardiovascular system, such as drug-resistant hypertension, tachycardia, significant headache, pallor, and sweating. Headache, hypokalemia and asthenia may also occur. In cases of hyperaldosteronism, on the other hand, the typical symptom is increased blood pressure, responsible for 1% of hypertension cases. In the most obvious cases (rare now) the condition can escalate to Cushing's syndrome, with the characteristic dorsal hump, moon-shaped face and striae rubra. These patients are at higher risk of hypertension, obesity, diabetes, dyslipidaemia, osteopenia and osteoporosis. In most cases, patients have symptoms associated with increased secretion of glucocorticoids. In the case of secreting lesions, symptoms depend on the type of hormone secreted: In these cases, the nodular lesions are called 'incidentalomas' with the prevalence of 1-6% in adult population. Most adrenal nodular lesions are not secreting and are sometimes discovered by the patient during diagnostic examinations for other problems. ![]() Whether an adrenal mass is symptomatic or not depends on its ability to release hormones into the systemic circulation. ![]()
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